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Article

Study of vitamin D status and vitamin D receptor polymorphisms in a cohort of Italian patients with juvenile idiopathic arthritis.

Scientific reports - 16 Oct 2020

Marini Francesca, Falcini Fernanda, Stagi Stefano, Fabbri Sergio, Ciuffi Simone, Rigante Donato, Cerinic Marco Matucci, Brandi Maria Luisa

Abstract excerpt

Juvenile idiopathic arthritis (JIA) is the most common chronic arthritis of children and adolescents. Autoimmune mechanisms are suspected to have a central role in its development. Vitamin D is an immuno-modulator in a variety of conditions, including autoimmune diseases. Low levels of vitamin D have commonly been found in JIA patients, but the influence of this hormone insufficiency in JIA pathogenesis is still...

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Identifiers

PMID: 33067526
DOI: 10.1038/s41598-020-74861-9
PMCID: PMC7567873

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