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Polymorphic Variants in the Vitamin D Receptor and Clinical Parameters of Rheumatoid Arthritis Patients Undergoing Anti-TNF Treatment.

Archivum immunologiae et therapiae experimentalis - 1 Jan 2024

Wielińska Joanna, Górna Katarzyna, Świerkot Jerzy, Bugaj Bartosz, Kolossa Katarzyna, Jeka Sławomir, Bogunia-Kubik Katarzyna

Abstract excerpt

Vitamin D levels have been related to the severity and progression of various autoimmune disorders. In this study, we aimed to investigate the impact of genetic variability in the vitamin D receptor (VDR) gene on disease susceptibility and progression in patients with rheumatoid arthritis (RA) treated with tumor necrosis factor (TNF) inhibitors. The study comprises 121 RA patients subjected to anti-TNF therapy...

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PMID: 39522115
DOI: 10.2478/aite-2024-0023

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