Article
Cytochrome p4501A1 gene variants as susceptibility marker for prostate cancer.
Cancer biomarkers : section A of Disease markers - 1 Jan 2005
Vijayalakshmi K, Vettriselvi V, Krishnan M, Shroff Sunil, Jayanth Vikram R, Paul Solomon F D
Abstract excerpt
CYP1A1 activates environmental procarcinogens and catalyzes oxidative metabolism of estrogens and is likely to play an important role in the etiology of prostate cancer. To evaluate this phenomenon, the association between two single nucleotide polymorphisms (A to G transition in exon7 leading to amino acid substitution Ile462Val and T3801C at 3'UTR) of CYP1A1 gene in prostate cancer were analyzed in a...
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