Article
Systemic sclerosis: the susceptible host (genetics and environment).
Rheumatic diseases clinics of North America - 1 May 2003
Tan Filemon K
Abstract excerpt
It is becoming evident that several genetic factors participate in modulating susceptibility to SSc and its clinical manifestations. Some genes that specifically affect ECM metabolism and vascular function may be unique to SSc and scleroderma-related disorders; others, such as those genes involved in regulating immune tolerance, are likely shared with other autoimmune diseases. The effect of genetic variations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.