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Article

Multiple defects of cell cycle checkpoints in U937-ASPI3K, an U937 cell mutant stably expressing anti-sense ATM gene cDNA.

Journal of Tongji Medical University = Tong ji yi ke da xue xue bao - 1 Jan 2000

Zhou J, Liu W, Sun L, Sun H, Tang Y

Abstract excerpt

(Ataxia-telangiectasia mutated gene (ATM) functions in control of cell cycle checkpoints in responding to DNA damage and protects cells from undergoing apoptosis. Knock-out within tumor cells of endogenous ATM will achieve therapeutic benefits and enable a better understanding of the decisive mec...

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Share to Ataxia Telangiectasia
Share to Ataxia Telangiectasia Mutated Proteins
Share to Cell Cycle

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Antisense

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Share to Genes, cdc

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Source

Identifiers

PMID: 12840909
DOI: 10.1007/BF02888177

Genes

ATM
CDK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12840909-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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Multiple defects of cell cycle checkpoints in U937-ASPI3K, an U937 cell mutant stably expressing anti-sense ATM gene cDNA.PMID 12840909Read ↗

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