Article
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation.
Molecular and cellular biology - 1 Feb 2002
Xu Bo, Kim Seong-Tae, Lim Dae-Sik, Kastan Michael B
Abstract excerpt
Cell cycle checkpoints are among the multiple mechanisms that eukaryotic cells possess to maintain genomic integrity and minimize tumorigenesis. Ionizing irradiation (IR) induces measurable arrests in the G(1), S, and G(2) phases of the mammalian cell cycle, and the ATM (ataxia telangiectasia mut...
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