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Article

Induction of DNA strand breaks by trihalomethanes in primary human lung epithelial cells.

Mutation research - 8 Jul 2003

Landi Stefano, Naccarati Alessio, Ross Matthew K, Hanley Nancy M, Dailey Lisa, Devlin Robert B, Vasquez Marie, Pegram Rex A, DeMarini David M

Abstract excerpt

Trihalomethanes (THMs) are disinfection by-products and suspected human carcinogens present in chlorinated drinking water. Previous studies have shown that many THMs induce sister chromatid exchanges and DNA strand breaks in human peripheral blood lymphocytes in vitro. Exposure to THMs occurs thr...

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Source

Identifiers

PMID: 12834753
DOI: 10.1016/s1383-5718(03)00086-x

Genes

GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12834753-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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