Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation of cytogenetic analysis and loss of heterozygosity studies in human diffuse astrocytomas and mixed oligo-astrocytomas.

Genes, chromosomes & cancer - 1 Nov 1992

Ransom D T, Ritland S R, Moertel C A, Dahl R J, O'Fallon J R, Scheithauer B W, Kimmel D W, Kelly P J, Olopade O I, Diaz M O

Abstract excerpt

The aims of this study were to correlate cytogenetic studies and molecular genetic loss of heterozygosity (LOH) analyses in human astrocytomas and mixed oligo-astrocytomas, and to locate putative tumor suppressor genes on chromosome 10. Paired blood and tumor samples from 53 patients were analyzed. The tumors included 45 diffuse astrocytomas (39 grade 4, 4 grade 3, and 2 grade 2), 1 astroblastoma, and 7 mixed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Aged, 80 and over

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Alleles

Share to Cell Transformation, Neoplastic

Share to Chromosome Aberrations

Share to DNA, Neoplasm

Share to DNA Probes

Share to Genetic Markers

Source

Identifiers

PMID: 1283325
DOI: 10.1002/gcc.2870050412

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation of cytogenetic analysis and loss of heterozygosity studies in human diffuse astrocytomas and mixed oligo-astrocytomas.PMID 1283325Read ↗

Loss of heterozygosity in malignant gliomas involves at least three distinct regions on chromosome 10Semantic proximity Read ↗

Reclassification of oligoastrocytomas by loss of heterozygosity studiesSemantic proximity Read ↗

Analysis of loss of heterozygosity for chromosome 10 in patients with malignant astrocytic tumors: correlation with patient age and survivalSemantic proximity Read ↗

p53 mutation and loss of heterozygosity on chromosomes 17 and 10 during human astrocytoma progression.Semantic proximity Read ↗

Allelotype of human malignant astrocytoma.Semantic proximity Read ↗

Chromosomal imbalances detected by array comparative genomic hybridization in human oligodendrogliomas and mixed oligoastrocytomasSemantic proximity Read ↗

Chromosome 10 and 17 deletions and p53 gene mutations in Thai patients with astrocytomas.Semantic proximity Read ↗

Loss of constitutional heterozygosity in chromosome 10 in human glioblastoma.Semantic proximity Read ↗

Allelic losses of chromosome 10 in glioma tissues detected by quantitative single-strand conformation polymorphism analysis.Semantic proximity Read ↗

Chromosome 7 Gain Compensates for Chromosome 10 Loss in GliomaSemantic proximity Read ↗

Chromosome 7 to the rescue: overcoming chromosome 10 loss in gliomasSemantic proximity Read ↗

Loss of heterozygosity for alleles on chromosome 10 in human brain tumours.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.