Article
Truncated forms of human and simian immunodeficiency virus in infected individuals and rhesus macaques are unique or rare quasispecies.
Virology - 20 Jun 2003
Pion Marjorie, Sanchez Giselle, Liska Vladimir, Bettendroffer Lise, Candotti Daniel, Chenine Agnès Laurence, Gondois-Rey Françoise, Tamalet Catherine, Vigne Robert, Ruprecht Ruth M, Agut Henri, Hirsch Ivan
Abstract excerpt
Truncated proviruses of variable sizes are present in peripheral blood mononuclear cells (PBMC) of human immunodeficiency virus type 1 (HIV-1)-infected persons and simian immunodeficiency virus (SIV)-infected rhesus macaques. Here, we investigated whether the highly deleted HIV and SIV proviruses are present in infected organisms as multiple copies or whether each truncated provirus is unique. Using end-point...
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