Article
A vaccine for tularaemia.
Expert opinion on biological therapy - 1 Jul 2003
Titball R W, Oyston P C F
Abstract excerpt
Francisella tularensis is an intracellular pathogen with a very low infectious dose for humans. Several forms of tularaemia occur, which range from a severely debilitating to a fatal disease. Diagnosis is difficult due to the generalised, nonspecific nature of symptoms and the difficulty in culturing the slow-growing and nutritionally fastidious pathogen. A live attenuated vaccine strain (LVS) has been used in...
Topics
- Animals
- Bacterial Vaccines
- Francisella tularensis
- Humans
- Mutation
- Tularemia
- Vaccines, Attenuated
