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Article

Several membrane polypeptides of the live vaccine strain Francisella tularensis LVS stimulate T cells from naturally infected individuals.

Journal of clinical microbiology - 1 Jan 1990

Sjöstedt A, Sandström G, Tärnvik A

Abstract excerpt

The currently used live vaccine strain Francisella tularensis LVS was derived several decades ago from a wild strain of the species. In the present report, several membrane polypeptides of LVS are shown to be recognized by T cells from individuals immunized by natural infection with F. tularensis. Bacterial membranes of a capsule-deficient mutant of LVS were subjected to sodium dodecyl sulfate-polyacrylamide gel...

Topics

Adult
Antigens, Bacterial
Bacterial Proteins
Bacterial Vaccines
Epitopes
Francisella tularensis
Humans
In Vitro Techniques
Lymphocyte Activation
Membrane Proteins
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

T-Lymphocytes

Tularemia

Source

Open in PubMed Open full text

Identifiers

PMID: 1688874
DOI: 10.1128/jcm.28.1.43-48.1990
PMCID: PMC269534

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1688874-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Several membrane polypeptides of the live vaccine strain Francisella tularensis LVS stimulate T cells from naturally infected individuals.PMID 1688874Read ↗

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