Article
Mouse V alpha 14i natural killer T cells are resistant to cytokine polarization in vivo.
Proceedings of the National Academy of Sciences of the United States of America - 8 Jul 2003
Matsuda Jennifer L, Gapin Laurent, Baron Jody L, Sidobre Stéphane, Stetson Daniel B, Mohrs Markus, Locksley Richard M, Kronenberg Mitchell
Abstract excerpt
Under different circumstances, natural killer T (NKT) cells can cause a T helper (Th) 1 or a Th2 polarization of immune responses. We show here, however, that mouse NKT cells with an invariant V alpha 14 rearrangement (V alpha 14i NKT cells) rapidly produce both IL-4 and IFN-gamma, and this patte...
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