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Article

Glutathione S-transferase genotypes, genetic susceptibility, and outcome of therapy in childhood acute lymphoblastic leukemia.

Blood - 1 Jul 2002

Davies Stella M, Bhatia Smita, Ross Julie A, Kiffmeyer William R, Gaynon Paul S, Radloff Gretchen A, Robison Leslie L, Perentesis John P

Abstract excerpt

The glutathione S-transferase (GST) genes are involved in the metabolism of environmental carcinogens and of some classes of chemotherapy drugs. GSTM1 and GSTT1 genotypes are polymorphic in humans, and the phenotypic absence of enzyme activity is caused by a homozygous inherited deletion of the g...

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Source

Identifiers

PMID: 12070010
DOI: 10.1182/blood.v100.1.67

Genes

GSTM1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12070010-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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