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Article

Hyperproliferation and p53 status of lens epithelial cells derived from alphaB-crystallin knockout mice.

The Journal of biological chemistry - 19 Sept 2003

Bai Fang, Xi Jing Hua, Wawrousek Eric F, Fleming Timothy P, Andley Usha P

Abstract excerpt

alphaB-Crystallin, a major protein of lens fiber cells, is a stress-induced chaperone expressed at low levels in the lens epithelium and numerous other tissues, and its expression is enhanced in certain pathological conditions. However, the function of alphaB in these tissues is not known. Lenses of alphaB-/- mice develop degeneration of specific skeletal muscles but do not develop cataracts. Recent work in our...

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PMID: 12826669
DOI: 10.1074/jbc.M304010200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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