Article
Higher stromal expression of transforming growth factor-beta type II receptors is associated with poorer prognosis breast tumors.
Breast cancer research and treatment - 1 May 2003
Barlow John, Yandell David, Weaver Donald, Casey Theresa, Plaut Karen
Abstract excerpt
Transforming growth factor-beta (TGFB) is a potent inhibitor of normal epithelial cell proliferation, and may be one of the regulatory factors that are perturbed during tumor development. While many tumor cell lines no longer respond to the inhibitory effects of TGFB due to a reduction or absence...
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