Article
Identification of an amino acid responsible for the CD3 polymorphism in cynomolgus monkeys (Macaca fascicularis).
Journal of medical primatology - 1 Apr 2003
Uda A, Tanabayashi K, Mukai R, Terao K, Yamada A
Abstract excerpt
The FN18 monoclonal antibody (mAb), directed to CD3 molecules, did not react with the lymphocytes of some cynomolgus monkeys (Macaca fascicularis), because of the polymorphism of the CD3epsilon chain. The epitope recognized by the FN18 mAb was successfully expressed on COS7 cells upon transfectio...
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