Article
Covalent and selective immobilization of fusion proteins.
Journal of the American Chemical Society - 2 Jul 2003
Kindermann Maik, George Nathalie, Johnsson Nils, Johnsson Kai
Abstract excerpt
A general method for the covalent immobilization of fusion proteins is presented. The approach is based on the unusual mechanism of the human O6-alkylguanine-DNA alkyltransferase, which irreversibly transfers the alkyl group from its substrate, alkylated or benzylated guanine, to a reactive cyste...
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