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Article

Ribosomal mutations conferring resistance to macrolides in Streptococcus pneumoniae clinical strains isolated in Germany.

Antimicrobial agents and chemotherapy - 1 Jul 2003

Reinert Ralf René, Wild Angela, Appelbaum Peter, Lütticken Rudolf, Cil Murat Yücel, Al-Lahham Adnan

Abstract excerpt

Among a collection of 4281 pneumococcal isolates, 7 strains isolated in Germany had an unusual macrolide resistance phenotype. The isolates were found to have multiple mutations in the 23S rRNA and alterations in the L4 ribosomal protein. One strain had an amino acid alteration in the L22 ribosomal protein.

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12821488
DOI: 10.1128/AAC.47.7.2319-2322.2003
PMCID: PMC161879

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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