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Article

Resistance to macrolides in clinical isolates of Streptococcus pyogenes due to ribosomal mutations.

The Journal of antimicrobial chemotherapy - 1 Jun 2002

Malbruny Brigitte, Nagai Kensuke, Coquemont Maëlle, Bozdogan Bülent, Andrasevic Arjana Tambic, Hupkova Helena, Leclercq Roland, Appelbaum Peter C

Abstract excerpt

OBJECTIVE: Two clinical strains of Streptococcus pyogenes, 237 and 544, one isolated in Slovakia and the other in Croatia, that were resistant to azithromycin (MIC 8 and 2 mg/L, respectively) but susceptible to erythromycin (MIC 0.5 and 0.12 mg/L, respectively) did not contain any gene known to confer macrolide resistance by ribosomal modification (erm gene) or efflux [mef(A) and msr(A) genes]. The aim of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12039885
DOI: 10.1093/jac/dkf038

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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