Article
Macrolide Resistance in Streptococcus pneumoniae.
Frontiers in cellular and infection microbiology - 1 Jan 2016
Schroeder Max R, Stephens David S
Abstract excerpt
Streptococcus pneumoniae is a common commensal and an opportunistic pathogen. Suspected pneumococcal upper respiratory infections and pneumonia are often treated with macrolide antibiotics. Macrolides are bacteriostatic antibiotics and inhibit protein synthesis by binding to the 50S ribosomal subunit. The widespread use of macrolides is associated with increased macrolide resistance in S. pneumoniae, and the...
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