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Article

Two new mechanisms of macrolide resistance in clinical strains of Streptococcus pneumoniae from Eastern Europe and North America.

Antimicrobial agents and chemotherapy - 1 Dec 2000

Tait-Kamradt A, Davies T, Appelbaum P C, Depardieu F, Courvalin P, Petitpas J, Wondrack L, Walker A, Jacobs M R, Sutcliffe J

Abstract excerpt

Resistance to macrolides in pneumococci is generally mediated by methylation of 23S rRNA via erm(B) methylase which can confer a macrolide (M)-, lincosamide (L)-, and streptogramin B (S(B))-resistant (MLS(B)) phenotype or by drug efflux via mef(A) which confers resistance to 14- and 15-membered m...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to RNA, Ribosomal, 23S

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Source

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Identifiers

PMID: 11083646
DOI: 10.1128/AAC.44.12.3395-3401.2000
PMCID: PMC90211

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-11083646-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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