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Article

The characterization and role of regulatory T cells in immune reactions.

Frontiers in bioscience : a journal and virtual library - 1 Jan 2008

Wilczynski Jacek R, Radwan Michal, Kalinka Jaroslaw

Abstract excerpt

Regulatory T cells (Tregs) having CD4+ CD25+ Foxp3+ or CD4+ IL-10+ (Tr1) phenotype and capable of inducing anergy towards self- and alloantigens play an important role in autoimmunity, as well as in tolerance of allografts, pregnancy and cancer. Both thymus-derived T CD4+ CD25+ Foxp3+ natural cells and peripherally-induced T CD4+ CD25+ Foxp3+ cells prevent migration of effector immunocytes to target organs and...

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Identifiers

PMID: 17981708
DOI: 10.2741/2840

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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