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Article

Association between myeloperoxidase and the risks of ischemic stroke, heart failure, and atrial fibrillation: A Mendelian randomization study.

Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Jan 2023

Wang Yinan, Jia Yiming, Xu Qingyun, Wang Ruirui, Sun Lulu, Guo Daoxia, Shi Mengyao, Yang Pinni, Wang Yu, Liu Fanghua, Zhang Yonghong, Zhu Zhengbao

Abstract excerpt

BACKGROUND AND AIMS: The causality between myeloperoxidase (MPO) and cardiovascular disease still remains unclear. We performed a two-sample Mendelian randomization (MR) study to estimate the potential causal effect of MPO on the risks of ischemic stroke, ischemic stroke subtypes, heart failure (HF), and atrial fibrillation (AF). METHODS AND RESULTS: Seventeen independent single-nucleotide polymorphisms...

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Identifiers

PMID: 36411224
DOI: 10.1016/j.numecd.2022.09.027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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