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Article

Inhibition of Graft-Versus-Host Disease by Double-Negative Regulatory T Cells

1 Jul 2003

Abstract excerpt

Pretransplant infusion of lymphocytes that express a single allogeneic MHC class I Ag has been shown to induce tolerance to skin and heart allografts that express the same alloantigens. In this study, we demonstrate that reconstitution of immunoincompetent mice with spleen cells from MHC class I L(d)-mismatched donors does not cause graft-vs-host disease (GVHD). Recipient mice become tolerant to skin allografts...

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Identifiers

PMID: 12816991
DOI: 10.4049/jimmunol.171.1.134

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Inhibition of Graft-Versus-Host Disease by Double-Negative Regulatory T CellsPMID 12816991Read ↗

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