Article
Family-based association study of schizophrenia with 444 markers and analysis of a new susceptibility locus mapped to 11q13.3.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 15 May 2004
Yamada K, Iwayama-Shigeno Y, Yoshida Y, Toyota T, Itokawa M, Hattori E, Shimizu H, Yoshikawa T
Abstract excerpt
Family-based linkage disequilibrium (LD) mapping has been suggested as a powerful and practical alternative to linkage analysis. We have performed a genome-wide LD survey of susceptibility loci for schizophrenia in a Japanese population. We first typed 119 schizophrenic pedigrees (357 individuals) using 444 microsatellite markers, and analyzed the data using the pedigree disequilibrium test. This analysis...
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