Article
CARD15/NOD2 analysis in rheumatoid arthritis susceptibility.
Rheumatology (Oxford, England) - 1 Nov 2003
Ferreirós-Vidal I, Barros F, Pablos J L, Carracedo A, Gómez-Reino J J, Gonzalez A
Abstract excerpt
OBJECTIVE: To determine if the mutations in the CARD15/NOD2 gene predisposing to Crohn's disease (CD) contribute also to the genetic susceptibility to rheumatoid arthritis (RA). METHODS: The frequencies of the three commonest mutations of CARD15/NOD2 predisposing to CD (2104C > T, 2722G>C and 3020insC) were determined in 210 RA patients and 227 controls. RESULTS: Allelic frequencies of the CARD15/NOD2 mutations...
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