Article
Fractalkine preferentially mediates arrest and migration of CD16+ monocytes.
The Journal of experimental medicine - 16 Jun 2003
Ancuta Petronela, Rao Ravi, Moses Ashlee, Mehle Andrew, Shaw Sunil K, Luscinskas F William, Gabuzda Dana
Abstract excerpt
CD16+ monocytes represent 5-10% of peripheral blood monocytes in normal individuals and are dramatically expanded in several pathological conditions including sepsis, human immunodeficiency virus 1 infection, and cancer. CD16+ monocytes produce high levels of proinflammatory cytokines and may represent dendritic cell precursors in vivo. The mechanisms that mediate the recruitment of CD16+ monocytes into tissues...
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