Article
Sequence polymorphisms in the apo(a) gene associated with specific levels of Lp(a) in plasma.
Human molecular genetics - 1 Feb 1995
Mooser V, Mancini F P, Bopp S, Pethö-Schramm A, Guerra R, Boerwinkle E, Müller H J, Hobbs H H
Abstract excerpt
Most of the interindividual variations in plasma levels of lipoprotein(a) [Lp(a)] can be attributed to sequence differences linked to the apolipoprotein(a) [apo(a)] locus. Plasma levels of Lp(a) tend to be inversely related to the number of kringle 4 (K4)-encoding sequences in the apo(a) gene, but there are several exceptions to this general trend. Other aspects of the apo(a) gene, in addition to the number of K4...
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