Sequence polymorphisms in the apo(a) gene associated with specific levels of Lp(a) in plasma.

doi:10.1093/hmg/4.2.173

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Article

Sequence polymorphisms in the apo(a) gene associated with specific levels of Lp(a) in plasma.

Human molecular genetics - 1 Feb 1995

Mooser V, Mancini F P, Bopp S, Pethö-Schramm A, Guerra R, Boerwinkle E, Müller H J, Hobbs H H

Abstract excerpt

Most of the interindividual variations in plasma levels of lipoprotein(a) [Lp(a)] can be attributed to sequence differences linked to the apolipoprotein(a) [apo(a)] locus. Plasma levels of Lp(a) tend to be inversely related to the number of kringle 4 (K4)-encoding sequences in the apo(a) gene, but there are several exceptions to this general trend. Other aspects of the apo(a) gene, in addition to the number of K4...

Topics

Alleles
Apolipoproteins A
Asian People
Base Sequence
Black People
DNA
Exons
Family Health
Genes, Reporter
Genome, Human
Humans
Introns

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lipoprotein(a)

Luciferases

Molecular Sequence Data

Polymerase Chain Reaction

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Source

Open in PubMed

Identifiers

PMID: 7757064
DOI: 10.1093/hmg/4.2.173

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7757064-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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