Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[The effect of gene polymorphism in promoter and intron 1 on human ApoA I expression].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Dec 2006

Cheng Ai-juan, Mao Yong-min, Cui Rang-zhuang

Abstract excerpt

OBJECTIVE: To construct pGL2-ApoA I luciferase reporter vector containing ApoA I gene regulation area, and to investigate the effect of G --> A and C --> T substitution in ApoA I promoter -75 bp and intron 1 +83 bp region respectively on ApoA I gene expression. METHODS: Human chromosome DNA fragments containing ApoA I gene were amplified by PCR, and the DNA fragments consisting of ApoA I AA/CC, GG/TT and GG/CC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoprotein A-I
Share to Cholesterol, HDL

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Vectors

Share to Introns

Share to Luciferases

Share to Point Mutation

Share to Recombinant Fusion Proteins

Share to Transfection

Source

Identifiers

PMID: 17160936

Genes

PRL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[The effect of gene polymorphism in promoter and intron 1 on human ApoA I expression].PMID 17160936Read ↗

[Influence of a G/A substitution at -75 bp promoter region of apolipoprotein A I gene and wine consumption on the plasma apolipoprotein A I levels in Yi and Han Chinese].Semantic proximity Read ↗

Studies of apolipoprotein (a) promoter from subjects with different plasma lipoprotein (a) concentrations.Semantic proximity Read ↗

A Promoter Polymorphism (Rs57137919) of ABCG1 Gene Influence on Blood Lipoprotein in Chinese Han Population.Semantic proximity Read ↗

[Variation of gene at the apolipoprotein C III locus with the changes of serum lipid profile in school-aged children].Semantic proximity Read ↗

[Effects of ApoE gene polymorphism on the efficacy of atorvastatin in the treatment of hyperlipidemia].Semantic proximity Read ↗

[Association between AvaII exon 13 polymorphism at the LDL receptor gene different and serum lipid levels in normotensives and essential hypertensives in Shanghai].Semantic proximity Read ↗

[Single nucleotide polymorphisms of genes associated with high density lipoprotein metabolism in Chinese population].Semantic proximity Read ↗

The analysis of APOL1 genetic variation and haplotype diversity provided by 1000 Genomes project.Semantic proximity Read ↗

The -250G-->A polymorphism in the human hepatic lipase gene promoter affects blood lipids in Chinese.Semantic proximity Read ↗

[Distribution of -477C/T single nucleotide polymorphism in the promoter region of ABCA1 gene and its significance for plasma lipids levels in normal Chinese Han population].Semantic proximity Read ↗

[Research progress of lipoprotein lipase gene].Semantic proximity Read ↗

[Apolipoprotein C gene and molecular biology].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.