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Article

False discovery rate in linkage and association genome screens for complex disorders.

Genetics - 1 Jun 2003

Sabatti Chiara, Service Susan, Freimer Nelson

Abstract excerpt

We explore the implications of the false discovery rate (FDR) controlling procedure in disease gene mapping. With the aid of simulations, we show how, under models commonly used, the simple step-down procedure introduced by Benjamini and Hochberg controls the FDR for the dependent tests on which linkage and association genome screens are based. This adaptive multiple comparison procedure may offer an important...

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Identifiers

PMID: 12807801
DOI: 10.1093/genetics/164.2.829
PMCID: PMC1462572

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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