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Article

Molecular dissection of the inward rectifier potassium current (IK1) in rabbit cardiomyocytes: evidence for heteromeric co-assembly of Kir2.1 and Kir2.2.

The Journal of physiology - 15 Jul 2003

Zobel Carsten, Cho Hee Cheol, Nguyen The-Tin, Pekhletski Roman, Diaz Roberto J, Wilson Gregory J, Backx Peter H

Abstract excerpt

Cardiac inward rectifier K+ currents (IK1) play an important role in maintaining resting membrane potential and contribute to late phase repolarization. Members of the Kir2.x channel family appear to encode for IK1. The purpose of this study was to determine the molecular composition of cardiac IK1 in rabbit ventricle. Western blots revealed that Kir2.1 and Kir2.2, but not Kir2.3, are expressed in rabbit...

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Identifiers

PMID: 12794173
DOI: 10.1113/jphysiol.2002.036400
PMCID: PMC2343053

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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