Article
Association studies between -1185A/G von Willebrand factor gene polymorphism and coronary artery disease.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas - 1 Jun 2003
Simon D, Paludo C A, Ghisleni G C, Manfroi W C, Roisenberg I
Abstract excerpt
High levels of von Willebrand factor (vWF) have been associated with cardiovascular disease. The A allele of the -1185A/G polymorphism in the 5'-regulatory region of the vWF gene was associated with the highest plasma vWF levels in a normal population. To examine the association between -1185A/G polymorphism and coronary artery disease (CAD), 173 Brazilian Caucasian subjects submitted to coronary angiography were...
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