Article
Association of the R485K polymorphism of the factor V gene with poor response to activated protein C and increased risk of coronary artery disease in the Chinese population.
Clinical genetics - 1 Apr 2000
Le W, Yu J D, Lu L, Tao R, You B, Cai X, Cao W J, Huang W, He R M, Zhu D L, Chen Z, Gong L S
Abstract excerpt
Inherited predisposition to thrombosis contributes to the initiation and progression of coronary artery disease (CAD). The present study was designed to explore the relationship between genetic variation of coagulation factor V and occurrence of CAD. A total of 141 unrelated patients with CAD and 175 healthy controls were analyzed by polymerase chain reaction-denaturing gradient gel electrophoresis (PCR-DGGE) for...
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