Article
Minimal residual disease in breast cancer and gynecological malignancies: phenotype and clinical relevance.
Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer - 1 Jan 2003
Roggel Frigga, Hocke Stefan, Lindemann Kristina, Sinz Sonja, Welk Anita, Bosl Martin, Pabst Martina, Nusser N, Braun Stephan, Schmitt Manfred, Harbeck Nadia
Abstract excerpt
In breast cancer, about 35% of patients without any clinical signs of overt distant metastases already have disseminated tumor cells in bone marrow aspirates at the time of primary therapy. A significant prognostic impact of these disseminated tumor cells has been shown by many international studies: patients with tumor cells in their bone marrow have a significantly worse prognosis than those without them. Even...
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