Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection and molecular characterisation of disseminated tumour cells: implications for anti-cancer therapy.

Biochimica et biophysica acta - 25 Sept 2005

Pantel Klaus, Woelfle Ute

Abstract excerpt

Haematogenous distant metastasis is the leading cause of cancer-related death in solid tumours. By applying sensitive immunocytochemical and molecular assays, disseminated tumour cells (DTC) in bone marrow (BM) can be detected in 20-40% of cancer patients without any clinical or even histopathological signs of metastasis, and the presence of these DTC at primary diagnosis predicts the subsequent occurrence of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Cells
Share to Bone Marrow Neoplasms
Share to Combined Modality Therapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diphosphonates

Share to DNA, Neoplasm

Share to Immunotherapy

Share to Neoplasm Invasiveness

Share to Neoplasm Metastasis

Source

Identifiers

PMID: 16099109
DOI: 10.1016/j.bbcan.2005.07.002

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection and molecular characterisation of disseminated tumour cells: implications for anti-cancer therapy.PMID 16099109Read ↗

Crucial roles of circulating tumor cells in the metastatic cascade and tumor immune escape: biology and clinical translationSemantic proximity Read ↗

Circulating and disseminated tumor cells: harbingers or initiators of metastasis?Semantic proximity Read ↗

Current and emerging concepts in tumour metastasisSemantic proximity Read ↗

Detection and clinical implications of early systemic tumor cell dissemination in breast cancer.Semantic proximity Read ↗

Targeting metastatic cancer.Semantic proximity Read ↗

Circulating tumor cell clusters: Insights into tumour dissemination and metastasisSemantic proximity Read ↗

Circulating tumor cells: detection, molecular profiling and future prospectsSemantic proximity Read ↗

The biology of circulating tumor cells.Semantic proximity Read ↗

Tracing the origins of metastasis.Semantic proximity Read ↗

Recent advances in understanding the complexities of metastasisSemantic proximity Read ↗

Unravelling the complexity of metastasis — molecular understanding and targeted therapiesSemantic proximity Read ↗

Circulating tumor cells: biology and clinical significanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.