Article
[Disseminated tumor cells: diagnosis, prognostic relevance, phenotyping and therapeutic strategies].
Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen - 1 Dec 1997
Pantel K, von Knebel Doeberitz M, Izbicki J R, Riethmüller G
Abstract excerpt
The incidence of local relapse after complete (R0) resection of solid tumors is largely determined by the skill of the surgeon, whereas metastatic relapse in distant organs is caused by pre- or perioperative systemic dissemination of tumor cells. The presence of individual disseminated tumor cells--e.g., in bone marrow as indicator organ--can be detected by sensitive immunocytochemical and molecular methods and...
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