Article
A new approach to phenotyping disseminated tumor cells: methodological advances and clinical implications.
The International journal of biological markers - 1 Jan 2000
Noack F, Schmitt M, Bauer J, Helmecke D, Krüger W, Thorban S, Sandherr M, Kuhn W, Graeff H, Harbeck N
Abstract excerpt
At the time of primary therapy (surgery, systemic chemotherapy and/or radiation), disseminated tumor cells in the bone marrow can be found in almost one-third of patients with cancer of the breast, ovary, esophagus, stomach, colon, and other solid tumors. Whereas the prognostic impact of the mere presence of these cells is still a matter of debate, it has been shown that expression of tumor-associated antigens in...
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