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Article

Control of signalling efficacy by palmitoylation of the rat Y1 receptor.

British journal of pharmacology - 1 Jun 2003

Holliday Nicholas D, Cox Helen M

Abstract excerpt

(1) We have investigated the properties of native and haemagglutinin (HA)-tagged neuropeptide Y (NPY) Y(1) receptors after mutation of the palmitoylation site Cys(337) to Ser or Ala. (2) In Chinese hamster ovary cells expressing similar receptor levels, the C337A mutation abolished incorporation of [(3)H]palmitic acid into the HA-Y(1) receptor. (3) Cys(337) substitution did not alter the affinities of Y(1)...

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Identifiers

PMID: 12788810
DOI: 10.1038/sj.bjp.0705276
PMCID: PMC1573875

Genes

PYY
NPY
VIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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