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Article

Identification of a D8S1179 primer binding site mutation and the validation of a primer designed to recover null alleles.

Forensic science international - 5 May 2003

Leibelt Craig, Budowle Bruce, Collins Patrick, Daoudi Yasser, Moretti Tamyra, Nunn Gary, Reeder Dennis, Roby Rhonda

Abstract excerpt

A population study of Chamorros and Filipinos using short tandem repeat (STR) loci amplified with the AmpFlSTR Profiler Plus PCR amplification kit demonstrated an excess of observed homozygosity at the D8S1179 locus. Use of a different set of D8S1179 primers to type the same samples did not demonstrate an excess of homozygosity and showed discordant genotypes at the D8S1179 locus. A single point mutation, G-to-A...

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PMID: 12787655
DOI: 10.1016/s0379-0738(03)00035-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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