Article
Large fragment Sanger sequencing identifies the newly encountered variant that caused null alleles in parentage testing.
International journal of legal medicine - 1 Jan 2023
Jiang Lanrui, Song Mengyuan, Wang Zefei, Wei Xiaowen, Zhou Yuxiang, Wang Shuangshuang, Zha Lagabaiyila, Song Feng, Luo Haibo
Abstract excerpt
Short tandem repeat (STR) is regarded as a crucial tool for personal identification as well as parentage testing. Thus, genotyping errors of STRs could have negative effects on the reliability of forensic identification. A null allele at the combined DNA index system (CODIS) core loci D2S1338 was found in a father-daughter pair with the AGCU Expressmarker 22 kit which was a commonly used commercial kit during our...
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