Article
Correction of bronchial challenge data for age and size may affect the results of genetic association studies in children.
Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology - 1 Jun 2003
Child Frances, Lenney Warren, Clayton Sadie, Davies Siobhan, Jones Peter W, Strange Richard C, Fryer Anthony A
Abstract excerpt
Meaningful studies of asthma genetics require careful definition of airway hyperresponsiveness (AHR). In children, several studies have emphasized the need for correction of bronchial challenge data for baseline parameters, such as age, gender, lung function and atopic status, when undertaking airway responsiveness measurements. However, few studies have suggested how this should be performed in practice. This...
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