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Article

Screening for bronchial hyperresponsiveness using methacholine and adenosine monophosphate. Relationship to asthma severity and beta(2)-receptor genotype.

American journal of respiratory and critical care medicine - 1 Oct 2000

Fowler S J, Dempsey O J, Sims E J, Lipworth B J

Abstract excerpt

Bronchial hyperresponsiveness (BHR) is a key feature of asthma and may be measured by direct methacholine challenge or indirect adenosine monophosphate (AMP) challenge. We performed a retrospective analysis of our database (n = 487) of patients with asthma with the aim first, to compare methacholine and AMP challenge as screening tools, and second, to identify any relationships between BHR and disease severity...

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Share to Adenosine Monophosphate
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Bronchial Hyperreactivity

Share to Bronchial Provocation Tests

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Share to Methacholine Chloride

Share to Predictive Value of Tests

Share to Receptors, Adrenergic, beta-2

Source

Identifiers

PMID: 11029338
DOI: 10.1164/ajrccm.162.4.9912103

Genes

FEV

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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