MECHANISM OF BONE FORMATION WITH GENE TRANSFER OF THE CDNA ENCODING FOR THE INTRACELLULAR PROTEIN LMP-1

Abstract excerpt

BACKGROUND: LIM mineralization protein-1 (LMP-1), an intracellular protein, is thought to induce secretion of soluble factors that convey its osteoinductive activity. Although evidence suggests that LMP-1 may be a critical regulator of osteoblast differentiation in vitro and in vivo, little is known about its mechanism of action. The purpose of the present study was to identify candidates for the induced secreted...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bone and Joint Diseases
• Share to Cell Adhesion Molecules Research
• Share to TGF-β signaling in diseases