Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpressed LIM mineralization proteins do not require LIM domains to induce bone.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Mar 2002

Liu Yunshan, Hair Gregory A, Boden Scott D, Viggeswarapu Manjula, Titus Louisa

Abstract excerpt

Rat LIM mineralization protein 1 (LMP-1, an LIM domain protein) mediates bone morphogenetic protein 6 (BMP-6) induction of bone nodule formation in fetal rat calvarial osteoblast (ROB) cultures. We have isolated the complementary DNA (cDNA) for the human homologue of LMP-1 from an adult human heart cDNA library and showed that when overexpressed it is osteoinductive in the same culture system. The recently...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Culture Media, Conditioned

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytoskeletal Proteins

Share to In Vitro Techniques

Share to Intracellular Signaling Peptides and Proteins

Share to LIM Domain Proteins

Share to Osteoblasts

Share to Tissue Distribution

Source

Identifiers

PMID: 11874232
DOI: 10.1359/jbmr.2002.17.3.406

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpressed LIM mineralization proteins do not require LIM domains to induce bone.PMID 11874232Read ↗

Truncated human LMP-1 triggers differentiation of C2C12 cells to an osteoblastic phenotype in vitro.Semantic proximity Read ↗

LIM mineralization protein-1 inhibits the malignant phenotypes of human osteosarcoma cells.Semantic proximity Read ↗

Characterization of a unique motif in LIM mineralization protein-1 that interacts with jun activation-domain-binding protein 1.Semantic proximity Read ↗

Characterization of tissue‐specific LIM domain protein (FHL1C) which is an alternatively spliced isoform of a human LIM‐only protein (FHL1)Semantic proximity Read ↗

Recql4 haploinsufficiency in mice leads to defects in osteoblast progenitors: Implications for low bone mass phenotype.Semantic proximity Read ↗

MECHANISM OF BONE FORMATION WITH GENE TRANSFER OF THE CDNA ENCODING FOR THE INTRACELLULAR PROTEIN LMP-1Semantic proximity Read ↗

Efficient bone formation by gene transfer of human LIM mineralization protein-3Semantic proximity Read ↗

Constitutive nuclear expression of dentin matrix protein 1 fails to rescue the Dmp1-null phenotype.Semantic proximity Read ↗

Analysis of a human cDNA containing a tissue-specific alternatively spliced LIM domain.Semantic proximity Read ↗

Tracing the pathway between mutation and phenotype in osteogenesis imperfecta: isolation of mineralization-specific genes.Semantic proximity Read ↗

USAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidneySemantic proximity Read ↗

Isolation of mouse and human cDNA clones encoding a protein expressed specifically in osteoblasts and brain tissuesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.