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Article

New paraoxonase 1 polymorphism I102V and the risk of prostate cancer in Finnish men.

Journal of the National Cancer Institute - 4 Jun 2003

Marchesani Marja, Hakkarainen Anna, Tuomainen Tomi-Pekka, Kaikkonen Jari, Pukkala Eero, Uimari Pekka, Seppälä Eija, Matikainen Mika, Kallioniemi Olli-P, Schleutker Johanna, Lehtimäki Terho, Salonen Jukka T

Abstract excerpt

BACKGROUND: Human serum paraoxonase eliminates carcinogenic lipid-soluble radicals. Because expression of the main human paraoxonase gene PON1 varies widely in humans, certain PON1 polymorphisms might be associated with increased risks of cancer. We sought new functional mutations in PON1 and determined whether known or new PON1 mutations were associated with the risk for prostate cancer in a prospective, random,...

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Identifiers

PMID: 12783936
DOI: 10.1093/jnci/95.11.812

Genes

PON1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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