Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Paraoxonase 1 (PON1) polymorphisms and prostate cancer in the CPS-II Nutrition Cohort.

The Prostate - 1 Sept 2008

Stevens Victoria L, Rodriguez Carmen, Talbot Jeffrey T, Pavluck Alexandre L, Thun Michael J, Calle Eugenia E

Abstract excerpt

BACKGROUND: The HDL-associated enzyme paraoxonase 1 acts to decrease oxidative stress, which is thought to contribute to cancer development. PON1, which encodes paraoxonase 1, has two common, nonsynonymous SNPs that alter the activity of this enzyme and may influence cancer risk. METHODS: We investigated the association the nonsynonymous SNPs, Q192R and L55M, with prostate cancer risk in a nested case-control...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Oxidative Stress
Share to Alleles
Share to Aryldialkylphosphatase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Case-Control Studies

Share to Cohort Studies

Share to Prostatic Neoplasms

Share to Reactive Oxygen Species

Share to United States

Source

Identifiers

PMID: 18500687
DOI: 10.1002/pros.20796

Genes

PON1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Paraoxonase 1 (PON1) polymorphisms and prostate cancer in the CPS-II Nutrition Cohort.PMID 18500687Read ↗

Differential effects of paraoxonase 1 (PON1) polymorphisms on cancer risk: evidence from 25 published studies.Semantic proximity Read ↗

The haplotypes of L55M and Q192R PON1 polymorphisms and the risk of prostate cancer.Semantic proximity Read ↗

Association of polymorphisms in the paraoxonase 1 gene with breast cancer incidence in the CPS-II Nutrition Cohort.Semantic proximity Read ↗

New paraoxonase 1 polymorphism I102V and the risk of prostate cancer in Finnish men.Semantic proximity Read ↗

PON1 polymorphisms are associated with polycystic ovary syndrome susceptibility, related traits, and PON1 activity in Indian women with the syndrome.Semantic proximity Read ↗

Paraoxonase 1 genetic polymorphisms and susceptibility to breast cancer: a meta-analysis.Semantic proximity Read ↗

A meta-analysis of the relationship between paraoxonase 1 polymorphisms and cancer.Semantic proximity Read ↗

Polymorphisms in oxidative stress pathway genes and prostate cancer risk.Semantic proximity Read ↗

A common genetic variation in paraoxonase 1 and risk of breast cancer: a literature review, meta-analysis, and in silico analysis.Semantic proximity Read ↗

Selenoprotein P genetic variants and mrna expression, circulating selenium, and prostate cancer risk and survival.Semantic proximity Read ↗

Appraising causal relationships of dietary, nutritional and physical-activity exposures with overall and aggressive prostate cancer: two-sample Mendelian-randomization study based on 79 148 prostate-cancer cases and 61 106 controlsSemantic proximity Read ↗

Interaction between single nucleotide polymorphisms in selenoprotein P and mitochondrial superoxide dismutase determines prostate cancer risk.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.