Article
[Association study between a polymorphism of aldosterone synthetase gene and the pathogenesis of polycystic ovary syndrome].
Zhonghua fu chan ke za zhi - 1 Feb 2003
Zhao Shu-ping, Tang Xiu-ming, Shao Dong-hong, Dai Hong-ying, Dai Shu-zhen
Abstract excerpt
OBJECTIVE: To investigate the relationship between -344T polymorphism in aldosterone synthetase (CYP11B2) gene promoter region and the pathogenesis of polycystic ovary syndrome (PCOS). METHODS: Ninety two patients with PCOS and controls were genotyped according to the fragment length (273 bp and or 202 bp) of CYP11B2 gene promoter by the technique of polymerase chain reaction-restriction fragment length...
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