Article
[Association between aldosterone synthase gene polymorphism and hypertrophic cardiomyopathy].
Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA - 1 Aug 2002
Chen Ai-Hua, Zhang Wen-Xiu, Li Zhi-Liang, Tang Xiao-Ming, Lu Qing, Qian Xue-Xian, Li Liu-Yang, Sun Jia-Zhen
Abstract excerpt
OBJECTIVE: To investigate the relationship between aldosterone synthase (CYP11B2) gene polymorphism and hypertrophic cardiomyopathy (HCM). METHODS: Fifteen HCM patients and 18 healthy subjects were enrolled in this study. Peripheral blood samples were collected from these subjects to exact genome DNA. PCR and Hae III restriction endonuclease digestion were employed to study -344C/T polymorphism of CYP11B2 gene....
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