Article
Gliotactin, a novel marker of tricellular junctions, is necessary for septate junction development in Drosophila.
The Journal of cell biology - 9 Jun 2003
Schulte Joost, Tepass Ulrich, Auld Vanessa J
Abstract excerpt
Septate junctions (SJs), similar to tight junctions, function as transepithelial permeability barriers. Gliotactin (Gli) is a cholinesterase-like molecule that is necessary for blood-nerve barrier integrity, and may, therefore, contribute to SJ development or function. To address this hypothesis, we analyzed Gli expression and the Gli mutant phenotype in Drosophila epithelia. In Gli mutants, localization of SJ...
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