Article
The IgLON protein Lachesin is required for the blood-brain barrier in Drosophila.
Molecular and cellular neurosciences - 1 Jan 2000
Strigini Maura, Cantera Rafael, Morin Xavier, Bastiani Michael J, Bate Michael, Karagogeos Domna
Abstract excerpt
In the mammalian peripheral nervous system, nerve insulation depends on the integrity of paranodal junctions between axons and their ensheathing glia. Ultrastructurally, these junctions are similar to the septate junctions (SJ) of invertebrates. In Drosophila, SJ are found in epithelia and in the glia that form the blood-brain barrier (BBB). Drosophila NeurexinIV and Gliotactin, two components of SJ, play an...
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